Anti-Human IL6R Recombinant Antibody (TAB-026) (CAT#: TAB-026)
Recombinant monoclonal antibody to Human IL6R. It is an immunosuppressive drug, mainly for the treatment of rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of RA in children. It is a humanized monoclonal antibody against the interleukin-6 receptor (IL-6R). Interleukin 6 (IL-6) is a cytokine that plays an important role in immune response and is implicated in the pathogenesis of many diseases, such as autoimmune diseases, multiple myeloma and prostate cancer.
Specific Inquiry
ELISA
Figure 1 Anti-Human IL6R Antibody (TAB-026) in ELISA
ELISA analysis of TAB-026 was performed by coating with Recombinant Human IL6R Protein.
WB
Figure 2 Anti-Human IL6R Antibody (TAB-026) in WB
Western blot analysis of TAB-026 was performed with Recombinant Human IL6R Protein.
Lane 1: Non-Reducing Antigen (1 μg)
Lane 2: Reducing Antigen (1 μg)
Specifications
- Immunogen
- IL-6R bound to Sepharose4B.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- IgG1, kappa
- Specificity
- Tested positive against native human antigen
- Species Reactivity
- Human, Cynomolgus
- Applications
- ELISA, FC, IP, FuncS, IF, Neut, ICC
- MW
- 145.0 kDa
- Related Disease
- Cytokine Release Syndrome (CRS), Systemic Juvenile Idiopathic Arthritis (sJIA), Giant Cell Arteritis (GCA), and Rheumatoid Arthritis (RA)
Product Property
- Purification
- Protein A purified
- Purity
- >95.0% as determined by analysis by SDS-PAGE.
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- The IL6R antibody has been reported in applications of Inhibition.
Target
- Alternative Names
- IL6R; interleukin 6 receptor; interleukin-6 receptor subunit alpha; CD126; IL-6R 1; CD126 antigen; membrane glycoprotein 80; IL-6 receptor subunit alpha; gp80; IL6RA; IL-6RA; IL-6R-1; IL6Q; gp80; CD126; HIES5; IL-6R; IL6RA; IL6RQ; IL-1Ra; IL-6RA; IL6QTL;
- Gene ID
- 3570
- UniProt ID
- P08887
Recommended Products
Isotype Control
Secondary Antibody
Related Resources
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Please refer to Tocilizumab-Atlizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Tocilizumab-Atlizumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1237z | Mouse Anti-IL6R Recombinant Antibody (clone 23B11) | ICC, IF, IHC, FC, IP, ELISA | Mouse IgG1 |
| MOB-2310MZ | Recombinant Mouse Anti-Human IL6R Antibody (clone C-O23) | FC, WB | Mouse antibody |
| HPAB-0251CQ | Human Anti-IL6R Recombinant Antibody (HPAB-0251CQ) | ELISA, FC, Block | Human IgG4 |
| HPAB-0165-YJ | Human Anti-IL6R Recombinant Antibody (HPAB-0165-YJ) | ELISA, Block, Inhib | Humanized IgG1, κ |
| HPAB-0612-WJ | Mouse Anti-IL6R Recombinant Antibody (HPAB-0612-WJ) | ELISA, FC | Mouse IgG1 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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